Gallbladder cancer in India has a notable geographic distribution, with higher incidence in northern states. Many cases are found incidentally, the histopathology after a routine laparoscopic cholecystectomy reveals invasive cancer. Stage is the dominant prognostic factor: early (T1a) disease is often cured by simple cholecystectomy alone, while T2 and beyond require radical re-resection (gallbladder bed, regional lymph nodes, sometimes bile duct or extended liver resection).
Condition
Gallbladder Cancer
Also known as: Carcinoma of the gallbladder
Aggressive cancer arising from the gallbladder lining, often associated with long-standing gallstone disease. Frequently found incidentally during routine cholecystectomy. Curative-intent surgery includes radical cholecystectomy with regional lymphadenectomy and partial liver resection.
Signs and symptoms
When to suspect gallbladder cancer
- Right upper abdominal pain (often persistent)
- Unintentional weight loss
- Loss of appetite
- Jaundice (yellow eyes/skin)
- Palpable mass in the right upper abdomen
- Persistent nausea
- Most early gallbladder cancers are asymptomatic, found on routine cholecystectomy histopathology
Risk factors
Who is at higher risk
- Female sex
- Age over 65
- Long-standing gallstone disease
- Porcelain gallbladder
- Gallbladder polyps over 1 cm
- Chronic typhoid carriers
- Geographic predisposition (north India, Chile, Japan)
- Family history
- Anomalous pancreaticobiliary duct junction
Surgical treatment options
Procedures Dr. Reddy performs for gallbladder cancer
Radical Cholecystectomy / Extended Hepatectomy
Gallbladder Cancer Surgery
Surgical treatment for gallbladder cancer, radical cholecystectomy, extended hepatectomy with lymphadenectomy, by Dr. Dwarakanath Reddy at Apollo Nellore. Multidisciplinary care.
Related conditions
Others in the same area of practice.
ICD-10 · C22
Liver Cancer (Hepatocellular Carcinoma)
Primary cancer of the liver, most commonly hepatocellular carcinoma (HCC) arising on a background of chronic liver disease. Curative options include resection (hepatectomy), ablation, or liver transplantation depending on stage and liver function.
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ICD-10 · C25
Pancreatic Cancer
Cancer of the pancreas, most commonly ductal adenocarcinoma. Aggressive and often diagnosed late. Curative-intent surgery (Whipple procedure for head tumours, distal pancreatectomy for body/tail) is possible in around 20 percent of cases.
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